The U.S. Health Coalition's message "Double Check, Don't Double Up" refers to which substance?

The message "Double Check, Don't Double Up" from the U.S. Health Coalition specifically targets APAP, also known as acetaminophen. This messaging is aimed at raising awareness among consumers about the potential risks of exceeding the recommended dosage of acetaminophen, which is commonly found in many over-the-counter medications.

People may inadvertently take multiple products containing acetaminophen simultaneously—such as a cold remedy and a pain reliever—leading to an increased risk of toxicity and liver damage. The slogan encourages individuals to carefully check the active ingredients of any medications they are taking to avoid unintentional overdosing of APAP.

While ibuprofen, aspirin, and codeine are important substances in their own right, they do not carry the same specific risk of accidental overdose associated with combining multiple medications containing acetaminophen. This focus on APAP is crucial for public health education related to safe medication practices.