What does the expiration date for solid or nonaqueous compounds depend on?

The expiration date for solid or nonaqueous compounds is primarily determined by the combination of the time remaining on the commercial product and a standard guideline that suggests a maximum time limit of six months from the date of compounding. This approach is essential because it ensures that the compounded preparation maintains its safety and efficacy throughout its use.

In the case of compounded medications, while the original expiration date of the active ingredients is an important consideration, it is not the sole factor. Compounded products may differ in stability once they are mixed, and therefore this combined approach helps pharmacists safeguard patients by ensuring that the compounded products are utilized within an appropriate timeframe.

Moreover, there are no inherent expiration limits established for solid or nonaqueous compounds through regulatory means, but relying solely on the original expiration date would fail to account for the nuances of compounding practices. As such, adhering to the guideline of six months or the remaining shelf life of any included commercial product provides a more effective measure for ensuring product quality.