What form is required to return a Schedule II (C2) controlled substance?

The requirement to use Form 222 for returning Schedule II controlled substances is grounded in federal regulations governing controlled substances. Form 222 serves as a controlled substance ordering and transferring document, which ensures proper tracking and accountability throughout the chain of custody for these highly regulated drugs.

When returning Schedule II substances, it is crucial to maintain a clear record to prevent misuse or diversion. The use of Form 222 creates a legal record of the transfer, detailing the items being returned, which is vital for both the pharmacy and the receiving entity, such as a reverse distributor, to ensure compliance with the Controlled Substances Act.

Utilizing a prescription pad for returning medications does not meet legal requirements, as it is intended for prescribing rather than for the documentation and transfer of controlled substances. Similarly, a return authorization form might not meet the specific federal requirements outlined for controlled substances, while the CSOS form is primarily utilized for electronic ordering rather than physical returns. Thus, the most appropriate and legally compliant method for returning Schedule II controlled substances is through the completion of Form 222.