What is a mandatory requirement for all prescriptions of controlled substances according to federal law?

The requirement that prescriptions for controlled substances must include cautionary statements is essential for safety and compliance with federal regulations. Cautionary statements are intended to inform the patient and the pharmacist regarding specific risks and necessary precautions associated with taking the prescribed medication, particularly for controlled substances that can have serious side effects or potential for abuse.

This is a critical aspect of patient care and medication management, as it ensures that important information is communicated effectively. Cautionary statements can educate patients on the proper use of their medication, potential interactions, and warnings that may prevent misuse.

In contrast, while insurance information, a doctor's signature on file, and writing prescriptions in ink may be important for other operational or regulatory purposes, they are not federally mandated requirements for all prescriptions of controlled substances, making cautionary statements the correct and vital component in this context.