Which of the following over-the-counter (OTC) medications must have child resistant closures?

The requirement for child-resistant closures for certain over-the-counter (OTC) medications is primarily rooted in safety regulations established to prevent accidental poisonings among children. In the context of OTC medications, acetaminophen is specifically recognized as a substance that requires child-resistant packaging due to its potential for overdose and serious consequences when ingested by young children. This specific regulation is part of guidelines enforced by federal law, particularly under the Poison Prevention Packaging Act.

While ibuprofen is also an OTC medication, the regulations regarding child-resistant packaging mainly focus on acetaminophen and other high-risk substances. Therefore, the requirement for child-resistant closures applies specifically to acetaminophen, making it necessary for proper safety measures to be implemented for this medication.

This focus on acetaminophen's safety in packaging underscores the public health approach to managing and mitigating risks associated with common household medications. It is essential for pharmacists and caregivers to be aware of such requirements to ensure that medications are stored and dispensed safely, reducing the risk to children.